Publications

High-content confocal analysis of tumorigenesis, cancer stem cells, and drug response in 3D cholangiocarcinoma cultures.

Kongtanawanich K, Jamnongsong S, Hokland M, Wattanapanitch M, Jirawatnotai S. Sci Rep. 2025 Aug 26;15(1):31387. doi: 10.1038/s41598-025-31387-x. PMID: 39587611

A chemically tunable FOXM1–DHFR sensor reveals the direct influence of FOXM1 on the cell cycle.

Phongkitkarun K, Chusorn P, Kamkaew M, Jamnongsong S, Lam EW, Promptmas C, Sampattavanich S. J Cell Sci. 2025 Jul 30;jcs-263749. doi: 10.1242/jcs.263749. PMID: 40586720 Free PMC article.

O‑GlcNAcylation as an emerging molecular target for cholangiocarcinoma therapy (Review).

Charoensuksai P, Jirawatnotai S. Oncol Rep. 2025 Jul 18;54(4):119. doi: 10.3892/or.2025.8952. PMID: 40682838; PMCID: PMC12308815 Free PMC article.

Curcumin for Inflammation Control in Individuals with Type 2 Diabetes Mellitus and Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomized Controlled Trial.

Yaikwawong M, Jansarikit L, Jirawatnotai S, Chuengsamarn S. Nutrients. 2025 Jun 10;17(12):1972. doi: 10.3390/nu17121972.

Vorinostat restores iNKT cell functionality in aggressive cholangiocarcinoma.

Htwe KSS, Soontrapa K, Prasopporn S, Chusorn P, Okada S, Jirawatnotai S, Sampattavanich S, Wongkajornsilp A. Biomedicine & Pharmacotherapy. 2025 May;186:117964. doi: 10.1016/j.biopha.2025.117964. PMID: 40101585 Free PMC article.

CAN-Scan: A multi-omic phenotype-driven precision oncology platform identifies prognostic biomarkers of therapy response for colorectal cancer.

Chia S, Seow JJW, Peres da Silva R, Suphavilai C, Shirgaonkar N, Murata-Hori M, Zhang X, Yong EY, Pan J, Thangavelu MT, Periyasamy G, Yap A, Anand P, Muliaditan D, Chan YS, Siyu W, Yong CW, Hong N, Ran G, Sim NL, Guo YA, Teh AXY, Ling CCW, Tan EKW, Cherylin FWP, Chang M, Han S, Seow-En I, Hui LRC, Gan AHH, Yap CK, Ng HH, Skanderup AJ, Chinswangwatanakul V, Riansuwan W, Trakarnsanga A, Pithukpakorn M, Tanjak P, Chaiboonchoe A, Park D, Kim DK, Iyer NG, Tsantoulis P, Tejpar S, Kim JE, Kim TI, Sampattavanich S, Tan IB, Nagarajan N, DasGupta R. Cell Reports Medicine. 2025 Apr 15;6(4):101260. doi: 10.1016/j.xcrm.2025.101260. PMID: 40187357; PMCID: PMC12047494.

Effectiveness of quality and quantity mononuclear cells for enhancing wound healing in diabetic ischemic limb animal model.

Sriphan P, Chruewkamlow N, Sathan-Ard C, Phutthakunphithak P, Sampattavanich S, Anekpuritanang T, Sakamula R, Likhityungyuen T, Wongwanit C, Ruangsetakit C, Sermsathanasawadi N. Int Wound J. 2025 Apr 7;22(4):e70106. doi: 10.1111/iwj.70106. PMID: 40192089 Free PMC article.

Exploring the Single-Cell Dynamics of FOXM1 Under Cell Cycle Perturbations.

Jawwad T, Kamkaew M, Phongkitkarun K, Chusorn P, Jamnongsong S, Lam EW-F, Sampattavanich S. Cell Proliferation. 2025 Mar 17;e70019. doi: 10.1111/cpr.70019. PMID: 40091487; PMCID: PMC12336449.

Durable and Drastic Response to the Trastuzumab, Letrozole, Abemaciclib, and Goserelin Combination as First-Line Therapy in HER2-Positive and Hormone Receptor-Positive Metastatic Breast Cancer: A Case Report.

Suwanvecho S, Kiatikajornthada N, Phikulsod P, Suwanrusme H, Jirawatnotai S. Case Rep Oncol. 2025 Jan 16;18(1):130-136. doi: 10.1159/000542926. PMID: 39980517; PMCID: PMC11487161 Free PMC article.

DNA damage response mutations enhance the antitumor efficacy of ATR and PARP inhibitors in cholangiocarcinoma cell lines.

Lerksuthirat T, Prasopporn S, Wikiniyadhanee R, Chitphuk S, Stitchantrakul W, Owneium P, Jirawatnotai S, Dejsuphong D. Oncol Lett. 2025 Jan 7;29(3):128. doi: 10.3892/ol.2025.14874. PMID: 39822940; PMCID: PMC11736248 Free PMC article.

Clinical Applications and Outcomes of the Supraclavicular Osteocutaneous Flap for Head and Neck Reconstruction.

Tanjapatkul R, Raktasuvarna N, Jirawatnotai S, Voravitvet TY, Sriswadpong P. Otolaryngol Head Neck Surg. 2025 Jan;172(1):82-90. doi: 10.1002/ohn.959. Epub 2024 Oct 22. PMID: 39435624.

Identification of Transcriptional Regulators of Immune Evasion Across Cancers: An Alternative Immunotherapeutic Strategy for Cholangiocarcinoma.

Venkatraman S, Balasubramanian B, Kongpracha P, Yangngam S, Chuangchot N, Khanaruksombat S, Thongchot S, Suntiparpluacha M, Myint KZ, Soodvilai S, Janvilisri T, Jirawatnotai S, Thuwajit P, Thuwajit C, Meller J, Chutipongtanate S, Tohtong R. Cancers. 2024 Dec 17;16(24):4197. doi: 10.3390/cancers16244197. PMID: 39766097; PMCID: PMC11674842 Free PMC article.

Immunoarchitectural Pattern and Its Potential Prognostic Value in Mucoepidermoid Carcinoma.

Tran VNT, Ruangritchankul K, Nikitakis NG, Sampattavanich S, Ferreira JN, Chaisuparat R. Oral Diseases. 2024 Dec 9. doi: 10.1111/odi.15216. PMID: 39490654.

A prevalent caveolin-1 gene rs926198 variant is associated with type 2 diabetes mellitus in the Thai population.

Yaikwawong M, Ek-eudomsuk P, Sittithumcharee G, Anupunpisit V, Peerapatdit T, Deerochanawong C, Himathongkam T, Jirawatnotai S, Chuengsamarn S. Sci Rep. 2024 Nov 11;14(1):27616. doi: 10.1038/s41598-024-78534-9. PMID: 38858743; PMCID: PMC10897562. Free PMC article.

Exploiting acquired vulnerability to develop novel treatments for cholangiocarcinoma.

Areewong S, Suppramote O, Prasopporn S, Jirawatnotai S. Cancer Cell Int. 2024 Nov 5;24(1):362. doi: 10.1186/s12935-024-03548-2. PMID: 39501277; PMCID: PMC11539612 Free PMC article.

Hippo pathway in cancer cells induces NCAM1+αSMA+ fibroblasts to modulate tumor microenvironment.

Thinyakul C, Sakamoto Y, Shimoda M, Liu Y, Thongchot S, Reda O, Nita A, Sakamula R, Sampattavanich S, Maeda A, Chunthaboon P, Nduru D, Niimura M, Kanamori Y, Thuwajit P, Nakayama KI, Guan KL, Satou Y, Thuwajit C, Moroishi T. Commun Biol. 2024 Oct 17;7(1):1343. doi: 10.1038/s42003-024-07041-4. PMID: 39420139; PMCID: PMC11487161 Free PMC article.

The correlation between cellular O-GlcNAcylation and sensitivity to O-GlcNAc inhibitor in colorectal cancer cells.

Wongprayoon P, Pengnam S, Srisuphan R, Opanasopit P, Jirawatnotai S, Charoensuksai P. PLoS One. 2024 Oct 16;19(10):e0312173. doi: 10.1371/journal.pone.0312173. PMID: 39413067; PMCID: PMC11482669. Free PMC article.

Protective Effects of Keratinocyte-Derived GCSF and CCL20 on UVB-Induced Melanocyte Damage.

Jeayeng S, Saelim M, Muanjumpon P, Buraphat P, Kanchanapiboon P, Sampattavanich S, Panich U. Cells. 2024 Oct 8;13(19):1661. doi: 10.3390/cells13191661. PMID: 39404423 Free PMC article.

Curcumin extract improves beta cell functions in obese patients with type 2 diabetes: a randomized controlled trial.

Yaikwawong M, Jansarikit L, Jirawatnotai S, Chuengsamarn S. Nutr J. 2024 Oct 1;23(1):119. doi: 10.1186/s12937-024-01022-3. PMID: 39354480; PMCID: PMC11445938 Free PMC article.

A live single-cell reporter system reveals drug-induced plasticity of a cancer stem cell-like population in cholangiocarcinoma.

Kongtanawanich K, Prasopporn S, Jamnongsong S, Thongsin N, Payungwong T, Okada S, Hokland M, Wattanapanitch M, Jirawatnotai S. Sci Rep. 2024 Sep 30;14(1):22619. doi: 10.1038/s41598-024-73581-8. PMID: 39349745.

Trastuzumab, a monoclonal anti-HER2 antibody modulates cytotoxicity against cholangiocarcinoma via multiple mechanisms.

Panaampon J, Sungwan P, Fujikawa S, Sampattavanich S, Jirawatnotai S, Okada S. Int Immunopharmacol. 2024 Sep 10;138:112612. doi: 10.1016/j.intimp.2024.112612. Epub 2024 Jul 4. PMID: 38968862.

Curcumin Reduces Depression in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial.

Yaikwawong M, Jansarikit L, Jirawatnotai S, Chuengsamarn S. Nutrients. 2024 Jul 25;16(15):2414. doi: 10.3390/nu16152414. PMID: 39276143 Free article.

Reversal of iNKT cell dysfunction in cholangiocarcinoma.

Htwe KSS, Soontrapa K, Jirawatnotai S, Prasopporn S, More-Krong P, Sampattavanich S, Wongkajornsilp A. Cancer Res. 2024 Mar 15;84(6_Supplement):3600. doi: 10.1158/1538-7445.AM2024-3600.

Comparison of mutation landscapes of pretreatment versus recurrent squamous cell carcinoma of the oral cavity: The possible mechanism of resistance to standard treatment.

Payungwong T, Angkulkrerkkrai K, Chaiboonchoe A, Lausoontornsiri W, Jirawatnotai S, Chindavijak S. Cancer Rep (Hoboken). 2024 Mar 13;7(3):e2004. doi: 10.1002/cnr2.2004. PMID: 38477073; PMCID: PMC10935893 Free PMC article.

Novel Midkine Inhibitor Induces Cell Cycle Arrest and Apoptosis in Multiple Myeloma.

Cheevapruk K, Ueno M, Sungwan P, Sittithumcharee G, Kariya R, Sampattavanich S, Okada S. Anticancer Res. 2024 Mar;44(3):1023-1031. doi: 10.21873/anticanres.16897. PMID: 38423667

Cholangiocarcinoma: Recent Advances in Molecular Pathobiology and Therapeutic Approaches.

Khosla D, Misra S, Chu PL, Guan P, Nada R, Gupta R, Kaewnarin K, Ko TK, Heng HL, Srinivasalu VK, Kapoor R, Singh D, Klanrit P, Sampattavanich S, Tan J, Kongpetch S, Jusakul A, Teh BT, Chan JY, Hong JH. Cancers (Basel). 2024 Feb 16;16(4):801. doi: 10.3390/cancers16040801. PMID: 38398194; PMCID: PMC10887007.

Live-cell imaging unveils stimulus-specific dynamics of Nrf2 activation in UV-exposed melanoma cells: implications for antioxidant compound screening.

Htut NW, Onkoksoong T, Saelim M, Kueanjinda P, Sampattavanich S, Panich U. Free Radic Biol Med. 2024 Feb 1;211:1-11. doi: 10.1016/j.freeradbiomed.2023.11.028.

Identifying potential immuno-oncology targets in salivary gland mucoepidermoid carcinoma based on inflammatory status and treatment response.

Urumarudappa SKJ, Tran VNT, Oo HM, Suntiparpluacha M, Sampattavanich S, Rosa V, Ruangritchankul K, Ferreira JN, Chaisuparat R. J Oral Pathol Med. 2023 Oct;52(10):939-950. doi: 10.1111/jop.13488.

Corrigendum: Combining the SMAC mimetic LCL161 with Gemcitabine plus Cisplatin therapy inhibits and prevents the emergence of multidrug resistance in cholangiocarcinoma

Prasopporn S, Suppramote O, Ponvilawan B, Jamyuang C, Chanthercrob J, Chaiboonchoe A, More-Krong P, Kongsri K, Suntiparpluacha M, Chanwat R, Korphaisarn K, Okada S, Sampattavanich S, Jirawatnotai S. Front Oncol. 2023 Jan 6;12:1124912. doi: 10.3389/fonc.2022.1124912. PMID: 36686801 Free PMC article.

The KRAS-Mutant Consensus Molecular Subtype 3 Reveals an Immunosuppressive Tumor Microenvironment in Colorectal Cancer.

Tanjak P, Chaiboonchoe A, Suwatthanarak T, Acharayothin O, Thanormjit K, Chanthercrob J, Suwatthanarak T, Wannasuphaphol B, Chumchuen K, Suktitipat B, Sampattavanich S, Korphaisarn K, Pongpaibul A, Poungvarin N, Grove H, Riansuwan W, Trakarnsanga A, Methasate A, Pithukpakorn M, Chinswangwatanakul V. Cancers (Basel). 2023 Feb 8;15(4):1098. doi: 10.3390/cancers15041098. PMID: 36831441 Free PMC article.

Retrospective study of transcriptomic profiling identifies Thai triple-negative breast cancer patients who may benefit from immune checkpoint and PARP inhibitors.

Suntiparpluacha M, Chanthercrob J, Sa-Nguanraksa D, Sitthikornpaiboon J, Chaiboonchoe A, Kueanjinda P, Jinawath N, Sampattavanich S. PeerJ. 2023 Jun 12;11:e15350. doi: 10.7717/peerj.15350. PMID: 37334114; PMCID: PMC10269579.

BAIAP2L1 enables cancer cell migration and facilitates phospho-Cofilin asymmetry localization in the border cells.

Pipatpanyanugoon N, Wareesawetsuwan N, Prasopporn S, Poolex W, Pisitkun T, Kaewkong W, Sampattavanich S, Jirawatnotai S. Cancer Commun (Lond). 2022 Jan;42(1):75-79. doi: 10.1002/cac2.12239. Epub 2021 Nov 23. PMID: 34811939 Free PMC article. No abstract available.

Comprehensive drug response profiling and pan-omic analysis identified therapeutic candidates and prognostic biomarkers for Asian cholangiocarcinoma.

Jamnongsong S, Kueanjinda P, Buraphat P, Sakornsakolpat P, Vaeteewoottacharn K, Okada S, Jirawatnotai S, Sampattavanich S. iScience. 2022 Sep 23;25(10):105182. doi: 10.1016/j.isci.2022.105182. eCollection 2022 Oct 21. PMID: 36248745 Free PMC article. https://pubmed.ncbi.nlm.nih.gov/33339185/

The Acquired Vulnerability Caused by CDK4/6 Inhibition Promotes Drug Synergism Between Oxaliplatin and Palbociclib in Cholangiocarcinoma.

Suppramote O, Prasopporn S, Aroonpruksakul S, Ponvilawan B, Makjaroen J, Suntiparpluacha M, Korphaisarn K, Charngkaew K, Chanwat R, Pisitkun T, Okada S, Sampattavanich S, Jirawatnotai S. Front Oncol. 2022 May 17;12:877194. doi: 10.3389/fonc.2022.877194. eCollection 2022. PMID: 35664774 Free PMC article.

Combining the SMAC mimetic LCL161 with Gemcitabine plus Cisplatin therapy inhibits and prevents the emergence of multidrug resistance in cholangiocarcinoma.

Prasopporn S, Suppramote O, Ponvilawan B, Jamyuang C, Chanthercrob J, Chaiboonchoe A, More-Krong P, Kongsri K, Suntiparpluacha M, Chanwat R, Korphaisarn K, Okada S, Sampattavanich S, Jirawatnotai S. Front Oncol. 2022 Nov 30;12:1021632. doi: 10.3389/fonc.2022.1021632. eCollection 2022. PMID: 36531039 Free PMC article.

Germline ATM mutation and somatic PIK3CA and BCOR mutations found in an infant with aggressive orbital embryonal rhabdomyosarcoma.

Jaru-Ampornpan P, Tansirisithikul C, Prukajorn M, Sampattavanich S, Pithukpakorn M. Am J Ophthalmol Case Rep. 2021 Aug 4;23:101189. doi: 10.1016/j.ajoc.2021.101189. eCollection 2021 Sep. PMID: 34401606 Free PMC article.

Novel Analytical Platform For Robust Identification of Cell Migration Inhibitors.

Somchai P, Phongkitkarun K, Kueanjinda P, Jamnongsong S, Vaeteewoottacharn K, Luvira V, Okada S, Jirawatnotai S, Sampattavanich S. Sci Rep. 2020 Jan 22;10(1):931. doi: 10.1038/s41598-020-57806-0. PMID: 31969633 Free PMC article.